Disease Areas of Collaborative Focus

Disease Areas

Arthritis

Assess your potential/novel therapeutics for efficacy and mechanism of action in BioModels’ established preclinical arthritis models. Our broad offering of rodent models of arthritis captures a spectrum of disease mechanisms and phenotypes. The BioModels team can work with you to help select the best model based on your potential targets and study goals.

Our literature-validated experimental endpoints include:

  • Weight Loss & Survival
  • In-life Arthritis Severity Assessment
  • Paw Edema Assessment
  • Local and Systemic Cytokine Assessment
  • Gene Expression
  • Peripheral Lymphoid Organ Immunophenotyping (Flow Cytometry)
  • Custom Assays and Endpoints

Study Models

Type II Collagen-Induced Arthritis (CIA)

Type II Collagen-Induced Arthritis (CIA)

Collagen Antibody-Induced Arthritis (CAIA)

Collagen Antibody-Induced Arthritis (CAIA)

ACL Transection Model of Osteoarthritis (OA)

ACL Transection Model of Osteoarthritis (OA)

Daniel Lichtman

Managing Partner