Disease Areas of Collaborative Focus

DISEASE AREAS

Liver Fibrosis

Assess your experimental materials for efficacy and mechanism of action in BioModels’ established liver fibrosis models. Liver fibrosis is common outcome of a number of chronic liver diseases and if left untreated can lead to liver failure, liver cancer, and death. BioModels’ liver fibrosis models capture a spectrum of disease mechanisms, allowing you to select the model most relevant for your hypothesis. The BioModels team is experienced with numerous preclinical liver fibrosis models, including chronic carbon tetrachloride- and diet-induced in vivo models.

Experimental endpoints for these models include:

  • Histopathology and Immunohistochemistry
  • Serum Chemistry
  • Collagen Content of Liver
  • Custom Assays and Endpoints

Study Models

CCl4-Induced Liver Fibrosis

CCl4-Induced Liver Fibrosis

Diet-Induced NASH (AMLN/GAN)

Diet-Induced NASH (AMLN/GAN)

Daniel Lichtman

Managing Partner