Disease Areas of
Collaborative Focus

DISEASE AREAS

Radiation-Induced Dermatitis

Assess your novel therapeutics for efficacy and mechanism of action in our established dermatitis models to address unmet clinical needs for patients undergoing radiation therapy. Dermatitis is an umbrella term for a group of conditions that cause inflammation of the skin and is one of the most common side effects of radiotherapy for certain cancers. We offer both acute and fractionated mouse models of radiation induced dermatitis, which are well-established in the literature and provide clinically relevant disease phenotypes.

Our literature-validated experimental endpoints include:

  • Weight Loss & Survival
  • In-Life Dermatitis Assessment/Skin Redness Assessment
  • Local and Systemic Cytokine Assessment
  • Gene Expression
  • Peripheral Lymphoid Organ Immunophenotyping (Flow Cytometry)
  • Custom Assays and Endpoints

Study Models

Acute Radiation-Induced Dermatitis

Acute Radiation-Induced Dermatitis

Fractionated Radiation-Induced Dermatitis

Fractionated Radiation-Induced Dermatitis

Daniel Lichtman

Managing Partner