Genomics, Personalized Medicine, and Supportive Cancer Care

AuthorsStephen Sonis
PublishedMay 01, 2015
JournalAmerican Society of Clinical Oncology Educational Book


The successes of the Human Genome Project catalyzed the transition of genomics from the laboratory to the clinic. Over the past decade, there has been a proliferation of studies demonstrating the potential utility of various applications of genomics as a conduit to accelerate drug development, understand mechanism(s) of action, and personalize treatment. For patients with cancer, genomics-informed medicine has largely focused on issues associated with patients' malignancies. But with the recognition that genomics is also a pivotal contributor to risk of regimen-related toxicities and how patients respond to treatment, the chances for applying genomics to comprehensive cancer care are increasing.

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