Preclinical Animal Models of IBD, GVHD, and Pulmonary Disease

Presented By: Andrew Borkowski and Nicole Smith

Description:

Join BioModels’ Scientists, Andrew Borkowski, PhD and Nicole Smith, PhD, as they discuss a selection of key preclinical models of inflammatory disease, including models of Inflammatory Bowel Disease (IBD)/colitis, Graft vs Host Disease (GvHD), and pulmonary disease, focusing on the utility of clinically relevant endpoints that create highly translational models of human disease.

Predominantly inflammation driven diseases like acute lung injury, asthma, Crohn’s Disease, Ulcerative Colitis and Graft vs Host Disease impact a large and diverse patient population and present a major opportunity for innovation in drug discovery. BioModels has spent over 25 years optimizing disease modeling approaches in these (and other) indications to support our pharmaceutical and biotech clients in their efforts to bring novel therapies to the clinic. Our goal is to provide personalized service and consultation to design and execute the most predictive modeling experiments to support your research programs.

• Learn about translational and predictive animal models of Inflammatory Bowel Disease (IBD), Graft versus Host Disease (GVHD), and pulmonary disease
• Understand the basic components of a successful and comprehensive study design in these therapeutic areas
• Review the typical disease induction approach, disease kinetics, responses to standard of care therapies, and standard endpoints/outcomes that are assessed in these models
• Understand how you can work with BioModels to support your drug development efforts using either established disease models or validating new models and endpoints

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