Acute GVHD (Major MHC Mismatch) Model!

Interested in evaluating your therapeutic in a preclinical model of GVHD? Assess your experimental materials for efficacy and mechanism of action in our established rodent models. BioModels’ GVHD models allow you to evaluate the immunopathology of post-transplant disease in various organs such as skin, gut, liver, and lung.

The BioModels team is experienced with multiple GVHD model induction paradigms:

• Acute GVHD (Major MHC Mismatch)
• Sclerodermatous Chronic GVHD (Minor MHC Mismatch)
• Humanized GVHD (PBMC Xenograft- xGVHD)
• Graft vs Leukemia (GVL)

Below please find data on our acute GVHD model. For additional information on our other models and/or to discuss your study needs, please email info@biomodels.com.

We look forward to connecting!

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