BioModels
Resource Center

๐—ช๐—ต๐—ผ ๐—ถ๐˜€ ๐—•๐—ถ๐—ผ๐— ๐—ผ๐—ฑ๐—ฒ๐—น๐˜€?

๐—œ๐—ป ๐˜€๐—ต๐—ผ๐—ฟ๐˜: ๐—ช๐—ต๐—ผ ๐—ถ๐˜€ ๐—•๐—ถ๐—ผ๐— ๐—ผ๐—ฑ๐—ฒ๐—น๐˜€, ๐—ฎ๐—ป๐—ฑ ๐˜„๐—ต๐—ฎ๐˜ ๐—ฑ๐—ผ ๐˜„๐—ฒ ๐—ฑ๐—ผ?
We’re a Boston-based preclinical CRO that helps biotechnology and pharmaceutical companies answer one critical question before moving into the clinic:

๐——๐—ผ๐—ฒ๐˜€ ๐˜๐—ต๐—ถ๐˜€ ๐˜๐—ต๐—ฒ๐—ฟ๐—ฎ๐—ฝ๐˜† ๐˜„๐—ผ๐—ฟ๐—ธ, ๐—ฎ๐—ป๐—ฑ ๐—ถ๐˜€ ๐—ถ๐˜ ๐—ฟ๐—ฒ๐—ฎ๐—ฑ๐˜† ๐˜๐—ผ ๐—บ๐—ผ๐˜ƒ๐—ฒ ๐˜๐—ผ๐˜„๐—ฎ๐—ฟ๐—ฑ ๐˜๐—ต๐—ฒ ๐—ฐ๐—น๐—ถ๐—ป๐—ถ๐—ฐ?
We design and execute predictive, translational, non-GLP efficacy studies in mice, rats, hamsters, and guinea pigs, partnering with clients from early discovery through IND-enabling research.

๐—ข๐˜‚๐—ฟ ๐—ฎ๐—ฟ๐—ฒ๐—ฎ๐˜€ ๐—ผ๐—ณ ๐—ฒ๐˜…๐—ฝ๐—ฒ๐—ฟ๐˜๐—ถ๐˜€๐—ฒ ๐—ถ๐—ป๐—ฐ๐—น๐˜‚๐—ฑ๐—ฒ:
๐Ÿงฌ ๐—œ๐—ป๐—ณ๐—น๐—ฎ๐—บ๐—บ๐—ฎ๐˜๐—ถ๐—ผ๐—ป & ๐—”๐˜‚๐˜๐—ผ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ฒ: IBD/colitis (DSS, TNBS, T-cell transfer), arthritis (CIA, CAIA), GVHD, dermatitis, asthma (OVA, HDM), EoE
๐Ÿซ ๐—™๐—ถ๐—ฏ๐—ฟ๐—ผ๐˜€๐—ถ๐˜€: IPF (bleomycin), liver (CClโ‚„), scleroderma
โ˜ข๏ธ ๐—ฅ๐—ฎ๐—ฑ๐—ถ๐—ฎ๐˜๐—ถ๐—ผ๐—ป: GI-ARS, TBI, fibrosis, mucositis, proctitis
โš–๏ธ ๐— ๐—ฒ๐˜๐—ฎ๐—ฏ๐—ผ๐—น๐—ถ๐—ฐ: Diet-induced obesity (DIO), MASH/NASH, diabetes, wound healing
๐ŸŽ—๏ธ ๐—ข๐—ป๐—ฐ๐—ผ๐—น๐—ผ๐—ด๐˜†: Xenograft, syngeneic, orthotopic, actinic keratosis, polyposis
๐Ÿง  ๐—ก๐—ฒ๐˜‚๐—ฟ๐—ผ๐˜€๐—ฐ๐—ถ๐—ฒ๐—ป๐—ฐ๐—ฒ: Behavior, addiction, autism, Parkinsonโ€™s, pain
๐ŸŒฌ๏ธ ๐—ฃ๐˜‚๐—น๐—บ๐—ผ๐—ป๐—ฎ๐—ฟ๐˜†: Acute lung injury (LPS), asthma, inhalation
๐Ÿฆ  ๐— ๐—ถ๐—ฐ๐—ฟ๐—ผ๐—ฏ๐—ถ๐—ผ๐—บ๐—ฒ ๐—ฅ๐—ฒ๐˜€๐—ฒ๐—ฎ๐—ฟ๐—ฐ๐—ต: Germ-free, gnotobiotic, infectious disease
๐Ÿ”ฌ ๐—–๐˜‚๐˜€๐˜๐—ผ๐—บ ๐— ๐—ผ๐—ฑ๐—ฒ๐—น ๐——๐—ฒ๐˜ƒ๐—ฒ๐—น๐—ผ๐—ฝ๐—บ๐—ฒ๐—ป๐˜: Surgical models, manuscript replication
๐Ÿงช ๐—œ๐—ป ๐—ฉ๐—ถ๐˜๐—ฟ๐—ผ/๐—˜๐˜… ๐—ฉ๐—ถ๐˜ƒ๐—ผ ๐—ฆ๐—ฒ๐—ฟ๐˜ƒ๐—ถ๐—ฐ๐—ฒ๐˜€: Cell culture, flow cytometry, Luminex, ELISA, qRT-PCR, microbiology

Whether you’re evaluating efficacy, optimizing study design, or developing a custom model, our team is here to help generate the data you need to move your program forward.

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Daniel Lichtman

Managing Partner