The spontaneous hypertension model can be used to evaluate the potential benefits of novel therapeutics, and drug combinations in reducing high blood pressure. Spontaneous hypertension is modeled using rodents that have a genetic predisposition to developing hypertension. Non-invasive blood pressure monitoring is employed to evaluate systolic blood pressure, diastolic blood pressure, mean arterial pressure, and heart rate.

• Mice (C3H, ICR, Ob/Ob, Db/Db)
• Rats (SHR, SHHF, SHROB, ZSF-1, and ZDF)

• In-life evaluation of blood pressure
• Heart rate

• Custom assays