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The diet-induced hypertension model can also be used to evaluate the potential benefits of novel therapeutics, and drug combinations in reducing high blood pressure. Hypertension is induced in Dahl-Salt Sensitive rats by a high salt diet. High blood pressure is observed from approximately 1 week on high salt diet. Non-invasive blood pressure monitoring is employed to evaluate systolic blood pressure, diastolic blood pressure, mean arterial pressure, and heart rate.
Blood pressure is monitored twice a week in Dahl-Salt sensitive rats using a non-invasive blood pressure system to measure mean arterial blood pressure (top), systolic blood pressure (middle) and diastolic blood pressure (bottom).
