Immunological Methods- Understanding and Enhancement of Preclinical Animal Models of Disease

Presented By: 
Dominic Beal

Overview: Aspects of both the innate and adaptive immune systems are involved in the vast majority of animal disease models. Knowledge of the immunological mechanisms involved in the pathogenesis of disease can therefore be used to great effect in the design and understanding of pre-clinical models of disease, and enhance their predictive value with respect to the development of novel therapeutics. The application of techniques such as flow cytometry, magnetic and fluorescence activated cell sorting, antigen/adjuvant exposure, and adoptive cell transfers has allowed for the generation of new models, as well as the enhancement and modification of existing models for specific purposes. This webinar discusses the application of these immunological methods and the advantages they provide in the setting of multiple validated pre-clinical animal models over a wide variety of disease platforms including GVHD, colitis, arthritis, and multiple sclerosis.

Request Slide Deck.