Design of Biomedical Robots for Phenotype Prediction Problems

AuthorsStephen Sonis, Enrique J. deAndres-Galiana, Juan Luis Fernandez-Martinez
PublishedAugust 27, 2016
JournalJournal of Computational Biology

Abstract:

Genomics has been used with varying degrees of success in the context of drug discovery and in defining mechanisms of action for diseases like cancer and neurodegenerative and rare diseases in the quest for orphan drugs. To improve its utility, accuracy, and cost-effectiveness optimization of analytical methods, especially those that translate to clinically relevant outcomes, is critical. Here we define a novel tool for genomic analysis termed a biomedical robot in order to improve phenotype prediction, identifying disease pathogenesis and significantly defining therapeutic targets.

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