Andrew W. Borkowski, Ph.D.

Scientist II


Dr. Borkowski joined Biomodels in 2017 as an Associate Scientist after completing his postdoctoral studies in the department of Immunology and Microbial Science at The Scripps Research Institute.  His postdoctoral work focused on elucidating novel mechanisms of wound healing based on the recognition of lipid antigens in the skin.  Andrew received his Ph.D. in Biomedical Sciences from the University of California, San Diego in 2014, where he discovered a role for toll-like receptor 3 in skin permeability barrier repair.  Dr. Borkowski has diverse interests in the field of immunology, including host-microbe interactions, the influence of the microbiome on human health, and the dynamics of physical and immunological barrier surfaces.  Andrew’s Biomodels’ portfolio focuses on projects associated with innate and adaptive immunity at barrier sites, and interventions targeting inflammatory and autoimmune disorders.


Publications by Andrew W. Borkowski, Ph.D.:

IL-1 Receptor-Knockout Mice Develop Epidermal Cysts and Show an Altered Innate Immune Response after Exposure to UVB Radiation

Non-coding Double-stranded RNA and Antimicrobial Peptide LL-37 Induce Growth Factor Expression from Keratinocytes and Endothelial Cells

Molecular cartography of the human skin surface in 3D

Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage

Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation, and epidermal organelles